CH 335 - Medicinal Chemistry

• Explain how molecular structure, biochemical reactions, and physicochemical parameters are highly relevant in medicinal chemistry research.
• Critically analyze and clearly articulate key research findings in primary scientific literature in drug discovery.
• Interpret SAR (structure-activity relationship) data and propose chemical modifications to address improvements in biological activity or pharmacokinetic properties of a potential drug.
• Examine drug-receptor interactions and enzyme inhibition/inactivation at the molecular level by utilizing computational molecular modeling tools.
• Propose the design and synthesis of a bioactive small molecule based on computational modeling data, synthetic organic chemistry, and the primary literature in drug discovery. 
• Clearly articulate the scientific background, results, data analysis, and conclusions by completing “peer-reviewed” scientific writing assignments and oral presentations.